Tom Lab

Studying how to promote functional recovery after spinal cord injury

June 2022

The Tom and One-Owusu Labs publish “Maladaptation of Renal Hemodynamics Contributes to Kidney Dysfunction Resulting from Thoracic Spinal Cord Injury in Mice” in The American Journal of Physiology - Renal Physiology. Congratulations, everyone! The PDF is available on the Publications page.

April 2022

The Tom Lab was awarded an R01 to study how to improve sympathetic regulation after spinal cord injury. Congrats to everyone!

April 2022

The Tom Lab (with Ashraful Islam as first author) publishes “The Use of Viral Vectors to Promote Repair After Spinal Cord Injury” in Experimental Neurology. This is Ash’s first as first author! Congrats! The PDF is available on the Publications page.

March 2022

Nishell Savory, a Neuroscience graduate student, joins the lab. Welcome, Nish!

December 2021

Ash Islam was awarded a Diversity Research Supplement to study how neuronal activation enhances axon regeneration after injury. Congratulations, Ash!

April 2021

Micaela O’Reilly was awarded an F31 from the NINDS to study the role of NFkB in sympathetic hyperreflexia after spinal cord injury. Congratulations on the achievement, Micaela!

March 2021

Mariah Wulf, a Neuroscience graduate student, officially joins the lab. Welcome, Mariah!

February 2021

The Tom and Bethea labs (with Micaela O’Reilly as first author) publish “Pharmacological Inhibition of Soluble Tumor Necrosis Factor-Alpha Two Weeks after High Thoracic Spinal Cord Injury Does Not Affect Sympathetic Hyperreflexia” in Journal of Neurotrauma. Congrats to the gang! The PDF is available on the Publications page.

December 2020

The Tom and Baas Labs (with Di Wu as first author) publish “Chronic neuronal activation increases dynamic microtubules to enhance functional axon regeneration after dorsal root crush injury” in Nature Communications. Well done, Di et al.! Di went out with a bang! The PDF is available on the Publications page.

September 2020

Despite being in the middle of a pandemic, we have fresh blood. Marisa Jeffries joins the lab as a postdoctoral fellow. Welcome, Marisa!

May 2020

The Tom Lab (with Micaela O’Reilly as first author) publishes “Neuroimmune System as a Driving Force for Plasticity Following CNS Injury” in Frontiers of Cellular Neuroscience. This is Micaela’s first as first author! Congrats! The PDF is available on the Publications page.

January 2020

The Tom and Hou labs publish “Grafting embryonic raphe neurons reestablishes serotonergic regulation of sympathetic activity to improve cardiovascular function after spinal cord injury” in The Journal of Neuroscience. Congratulations! The PDF is available on the Publications page.

January 2020

The Tom and Bethea labs publish “Attenuating neurogenic sympathetic hyperreflexia robustly improves antibacterial immunity after chronic spinal cord injury” in The Journal of Neuroscience (with Tom Lab alumnus Eugene Mironets as first author). Congrats, everyone! The PDF is available on the Publications page.

January 2020

The Tom lab’s R01 to study multi-pronged approaches to promote axon regeneration was renewed. Fantastic start to the year!

October 2019

The Tom and Bethea labs continue to have collaborative success and were awarded another multi-PI R01 to study how TNFa contributes to the perturbed antiviral immunity after SCI. Another round of huge thanks to the whole team for their hard work!

April 2019

Eugene Mironets successfully defended his PhD dissertation. Congratulations, Dr. Mironets!

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March 2019

The Baas and Tom Labs publish “Knockdown of Fidgetin Improves Regeneration of Injured Axons by a Microtubule-Based Mechanism” in The Journal of Neuroscience. Well done! The PDF is available on the Publications page.


October 2018

The Tom Lab did very well at Drexel’s annual Discovery Day! Micaela received Honorable Mention in the Outstanding Junior Graduate Student Poster category. Eugene received the Barry Waterhouse Outstanding Platform Presentation Award and the Bondi Fellowship. Wow! Congrats to you both!

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August 2018

Eugene Mironets was awarded a Drexel International Travel Award to present at the 14th Congress of the International Society of Neuroimmunology in Brisbane, Australia. Congratulations, Eugene!


May 2018

Micaela O’Reilly, first year Neuroscience graduate student, officially joins the lab. Welcome, Micaela! Here’s to many fruitful patches!


April 2018

The Tom and Bethea labs were awarded a multi-PI R01 to study how TNFa contributes to the development of autonomic dysreflexia after a spinal cord injury (with Kim Dougherty and Patrick Osei-Owusu as Co-Investigators). Thanks to the whole team for their hard work!

 

April 2018

The Tom Lab (with Eugene Mironets as first author) publishes, "Soluble TNFa signaling within the spinal cord contributes to the development of autonomic dysreflexia and ensuing vascular and immune dysfunction after spinal cord injury" in The Journal of Neuroscience. Congratulations to Eugene and gang! This is Eugene's first first author (yes, you read that correctly), primary research publication ever, which calls for a double congratulations! The PDF is available on the Publications page.

 

December 2017

The Tom Lab (with Di Wu as first author) publishes, "Combining constitutively active Rheb expression and chondroitinase promotes functional axonal regeneration after cervical spinal cord injury" in Molecular Therapy. Congrats to Di et al.!

 

October 2017

Eugene Mironets won 3rd place for Drexel's Discovery Day 2017 Outstanding Senior Graduate Student Poster (there were over 380 posters in consideration). Congrats, Eugene!

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July 2017

Eugene Mironets was awarded another year of a highly competitive Dean's Fellowship for Excellence in Collaborative or Themed Research for his ongoing project between the Tom, Bethea, and Osei-Owusu Labs. Congratulations, again, Eugene!

 

May 2017

Eileen Collyer joins the lab as a Postdoctoral Fellow. Bienvenida!

 

April 2017

Eugene Mironets successfully defended his Ph.D. thesis dissertation proposal and is officially a Ph.D. candidate. Congrats, Eugene!

 

December 2016

Shaoping Hou's recent publication was highlighted in the Research News blog on the Christopher and Dana Reeve Foundation's website.

https://www.christopherreeve.org/blog/research-news/spinal-cord-dopamine-linked-to-bladder-function

 

December 2016

Shaoping Hou, Research Assistant Professor, was awarded an R01 from NIH/NINDS to further explore the role or dopamine in bladder function after a spinal cord injury. Congratulations, Shaoping!

 

November 2016

The Tom Lab (with Shaoping Hou as first and co-corresponding author) publishes, "Dopamine is produced in the rat spinal cord and regulates micturition reflex after spinal cord injury" in Experimental Neurology. Congratulations to all involved! The PDF is available on the Publications page.

 

July 2016

The Tom Lab (with Di Wu as first author) publishes, "Expressing constitutively active Rheb in adult dorsal root ganglion neurons enhances the integration of sensory axons that regenerate across a chondroitinase-treated dorsal root entry zone following dorsal root crush" in Frontiers in Molecular Neuroscience. Congrats Di and company! The PDF is available on to the Publications page. 

 

July 2016

The Tom Lab received a Craig H. Neilsen Foundation award to study the role of TNFa in the development of autonomic dysreflexia in collaboration with Dr. Patrick Osei-Owusu and Dr. John Bethea. Thanks to everyone in the lab for their hard work!

 

May 2016

The Tom Lab welcomes undergraduate students Ioanna Yiantsos (Temple) and Benjamin Murray (Emory) to work in the lab over the summer.  It's Ben's second stint in the lab so I guess we're not so bad.  Have fun!

 

May 2016

The Tom Lab has a new member of the family.  Welcome to the world, Yoyoung Lu!  Congratulations, Di!

 

May 2016

Eugene Mironets, second year graduate student, was awarded a Dean's Fellowship for Excellence in Collaborative or Themed Research for his project between the Tom, Bethea, and Osei-Owusu Labs. Congrats, Eugene (and James)! 

 

March 2016

The Tom Lab publishes, "Manipulating extrinsic and intrinsic obstacles to axonal regeneration after spinal cord injury" in Neural Regeneration Research. The PDF is available on our Publications page.

 

March 2016

The Tom Lab publishes, "Cardiovascular dysfunction following spinal cord injury" in Neural Regeneration Research. Go to our Publications page for the PDF.

 

January 2016

Shaoping Hou was awarded a grant from the Morton Cure Paralysis Fund for his project "Targeting spinal dopaminergic regulation to improve micturition recovery after spinal cord injury". Congrats, Shaoping!

 

October 2015

Tatiana Saltos joins the lab as a Research Assistant. Welcome, Tatiana!

 

October 2015

Eugene Mironets received 2nd place for Junior Graduate Student Poster Presentation at Drexel University College of Medicine's Discovery Day. Congratulations, Eugene!


August 2015

Di Wu's recent publication in The Journal of Neuroscience was highlighted in the Research News blog on the Christopher and Dana Reeve Foundation's website.

http://www.spinalcordinjury-paralysis.org/blogs/18/2572  


August 2015

The Tom Lab publishes "Expressing constitutively active Rheb in adult neurons after a complete spinal cord injury enhances axonal regeneration beyond a chondroitinase-treated glial scar" in The Journal of Neuroscience. Go to our Publications page for the PDF.


June 2015

Benjamin Murray, a Drexel University Summer Undergraduate Research Fellow from Emory University, joins the lab for the summer. Welcome, Ben!


May 2015

Eugene Mironets, a first year Neuroscience graduate student, officially joins the lab. Welcome, Eugene!